Ass.-Prof. Dr. Florian Kopp
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Publications
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Journal Articles
Elguindy MM, Kopp F, Goodarzi M, Rehfeld F, Thomas A, Chang TC, Mendell JT. PUMILIO, but Not RBMX, Binding Is Required for Regulation of Genomic Stability by Noncoding RNA NORAD. eLife. 2019. http://doi.org/10.7554/eLife.48625
Kopp F. Molecular functions and biological roles of long non‐coding RNAs in human physiology and disease. J. Gene Med. 2019. https://doi.org/10.1002/jgm.3104
Kopp F, Elguindy MM, Yalvac ME, Zhang H, Chen B, Gillett FA, Lee S, Sivakumar S, Yu H, Xie Y, Mishra P, Sahenk Z, Mendell JT. PUMILIO Hyperactivity Drives Premature Aging of Norad-deficient Mice. eLife. 2019. http://doi.org/10.7554/eLife.42650
Kopp F, Mendell JT. Functional Classification and Experimental Dissection of Long Noncoding RNAs. Cell 2018. http://doi.org/10.1016/j.cell.2018.01.011
Golden RJ, Chen B, Li T, Braun J, Manjunath H, Chen X, Wu J, Schmid V, Chang TC, Kopp F, Ramirez-Martinez A, Tagliabracci VS, Chen ZJ, Xie Y, Mendell JT. An Argonaute Phosphorylation Cycle Promotes microRNA-mediated Silencing. Nature. 2017. http://doi.org/10.1038/nature21025
Lee S, Kopp F, Chang TC, Sataluri A, Chen B, Sivakumar S, Yu H, Xie Y, Mendell JT. Noncoding RNA NORAD Regulates Genomic Stability by Sequestering PUMILIO Proteins. Cell. 2016. http://doi.org/10.1016/j.cell.2015.12.017
Kopp F, Hermawan A, Oak PS, Ulaganathan VK, Herrmann A, Elnikhely N, Thakur C, Xiao Z, Knyazev P, Ataseven B, Savai R, Wagner E, Roidl A. Sequential Salinomycin Treatment Results in Resistance Formation Through Clonal Selection of Epithelial-Like Tumor Cells. Transl. Oncol. 2014. http://doi.org/10.1016/j.tranon.2014.09.002
Kopp F, Wagner E, Roidl A. The Proto-Oncogene KRAS Is Targeted by miR-200c. Oncotarget. 2014. http://doi.org/10.18632/oncotarget.1427
Kopp F, Hermawan A, Oak PS, Herrmann A, Wagner E, Roidl A. Salinomycin Treatment Reduces Metastatic Tumor Burden by Hampering Cancer Cell Migration. Mol. Cancer. 2014. http://doi.org/10.1186/1476-4598-13-16
Kopp F, Schnoedt M, Haase R, Wagner E, Roidl A, Ogris M. De-targeting by miR-143 Decreases Unwanted Transgene Expression in Non-Tumorigenic Cells. Gene Therapy. 2013. http://doi.org/10.1038/gt.2013.37
Haase R, Magnusson T, Su B, Kopp F, Wagner E, Lipps H, Baiker A, Ogris M. Generation of a tumor- and tissue-specific episomal non-viral vector system. BMC Biotechnol. 2013. http://doi.org/10.1186/1472-6750-13-49Oak PS, Kopp F, Thakur C, Ellwart JW, Rapp UR, Ullrich A, Wagner E, Knyazev P, Roidl A. Combinatorial Treatment of Mammospheres With Trastuzumab and Salinomycin Efficiently Targets HER2-positive Cancer Cells and Cancer Stem Cells. Int. J. Cancer. 2012. http://doi.org/10.1002/ijc.27595
Kopp F, Oak PS, Wagner E, Roidl A. miR-200c Sensitizes Breast Cancer Cells to Doxorubicin Treatment by Decreasing TrkB and Bmi1 Expression. PLoS One. 2012. http://doi.org/10.1371/journal.pone.0050469