Mag.pharm. Dr. Stefan Poschner
Contact
Mail: stefan.poschner @ univie.ac.at
Phone: +43-1-4277-55543
Fax: +43-1-4277-855543
Room: 2E252
Sprechstunde: nach vorheriger Vereinbarung (via e-Mail)
Research interests
- steroid metabolism in gynecological cancers (breast, ovary)
- interaction of dietary supplements with endogenous metabolic processes
- development and validation of HPLC-DAD, HPLC-HRMS and UPLC-HRMS methods for the identification and quantification of natural or pharmaceutical compounds
- quantification of pharmaceutical drugs in biological matrices (plasma, bile, CSF, microdialysate,...)
Publications
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Journal Articles - 2024
El Biali M, Wölfl-Duchek M, Jackwerth M, Mairinger S, Weber M, Bamminger K, Poschner S, Rausch I, Schindler N, Lozano IH, Jäger W, Nics L, Tournier N, Hacker M, Zeitlinger M, Bauer M, Langer O. Clin Transl Sci. 2024 May;17(5):e13804.
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Journal Articles - 2023
Al Jalali V, Bauer M, Wölfl-Duchek M, Sarhan M, Wicha SG, Poschner S, Jäger W, König F, Male C, Zeitlinger M, Clin Pharmacokinet. 2023 Jan;62(1):77-87.
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Journal Articles - 2022
Alshaer MH, Barlow B, Maranchick N, Moser M, Gramss L, Burgmann H, Jalali VA, Wölfl-Duchek M, Jäger W, Poschner S, Plöchl W, Reinprecht A, Rössler K, Gruber A, Zeitlinger M, Peloquin CA, Hosmann A, Antimicrob Agents Chemother. 2022 Aug 16;66(8):e0043822.
Büsker S, Jäger W, Poschner S, Mayr L, Al Jalali V, Gojo J, Azizi AA, Ullah S, Bilal M, El Tabei L, Fuhr U, Peyrl A, Cancer Chemother Pharmacol. 2022 May;89(5):617-627.
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Journal Articles - 2021
Pavlič R, Gjorgoska M, Hafner E, Sinreih M, Gajser K, Poschner S, Jäger W, Rižner TL, Front Mol Biosci. 2021 Nov 5;8:743403.
Meropenem concentrations in brain tissue of neurointensive care patients exceed CSF levels
Hosmann A, Ritscher L, Burgmann H, Al Jalali V, Wulkersdorfer B, Wölfl-Duchek M, Sanz Codina M, Jäger W, Poschner S, Plöchl W, Reinprecht A, Rössler K, Gruber A, Zeitlinger M, J Antimicrob Chemother. 2021 Aug 15:dkab286.
Pavlič R, Vidic S, Anko M, Knific T, Büdefeld T, Marton K, Sinreih M, Poschner S, Jäger W, Frković-Grazio S, Rižner TL, Int J Mol Sci. 2021 Apr 7;22(8):3819.
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Journal Articles - 2020
Poschner S, Wackerlig J, Dobusch D, Pachmann B, Banh SJ, Thalhammer T, Jäger W, Phytomedicine. 2020 Sep 25;79:153357.
Racova Z, Anzenbacherova E, Papouskova B, Poschner S, Kucova P, Gausterer JC, Gabor F, Kolar M, Anzenbacher P, J Nutr Biochem. 2020 Aug 12;85:108482.
Poschner S, Wackerlig J, Castillo-Tong DC, Wolf A, Decken IV, Rižner TL, Pavlič R, Meshcheryakova A, Mechtcheriakova D, Fritzer-Szekeres M, Thalhammer T, Jäger W, Cancers (Basel). 2020 Jan 23;12(2). pii: E279.
Impact of thrombocytes, on bacterial growth and antimicrobial activity of selected antibiotics
Nussbaumer-Pröll AK, Eberl S, Reiter B, Stimpfl T, Jäger W, Poschner S, Zeitlinger M, Eur J Clin Microbiol Infect Dis. 2020 Mar;39(3):593-597.
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Journal Articles - 2019
Poschner S, Maier-Salamon A, Thalhammer T, Jäger W, J Steroid Biochem Mol Biol. 2019 Mar 6;190:11-18.
Impact of erythrocytes on bacterial growth and antimicrobial activity of selected antibiotics
Nussbaumer-Pröll AK, Knotzer S, Eberl S, Reiter B, Stimpfl T, Jäger W, Poschner S, Zeitlinger M, Eur J Clin Microbiol Infect Dis. 2019 Mar;38(3):485-495.
Traxl A, Mairinger S, Filip T, Sauberer M, Stanek J, Poschner S, Jäger W, Zoufal V, Novarino G, Tournier N, Bauer M, Wanek T, Langer O, Mol Pharm. 2019 Mar 4;16(3):1282-1293.
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Journal Articles - 2018
Bauer M, Karch R, Wulkersdorfer B, Philippe C, Nics L, Klebermass EM, Weber M, Poschner S, Haslacher H, Jäger W, Tournier N, Wadsak W, Hacker M, Zeitlinger M, Langer O, J Nucl Med. 2018 Sep 20. pii: jnumed.118.216432.
Bauer M, Traxl A, Matsuda A, Karch R, Philippe C, Nics L, Klebermass EM, Wulkersdorfer B, Weber M, Poschner S, Tournier N, Jäger W, Wadsak W, Hacker M, Wanek T, Zeitlinger M, Langer O, Mol Pharm. 2018 Oct 1;15(10):4589-4598.
Poschner S, Maier-Salamon A, Zehl M, Wackerlig J, Dobusch D, Meshcheryakova A, Mechtcheriakova D, Thalhammer T, Pachmann B, Jäger W, Front Pharmacol. 2018 Jul 10;9:742.
Concentrations of Cefuroxime in Brain Tissue of Neurointensive Care Patients
Hosmann A, Ritscher LC, Burgmann H, Oesterreicher Z, Jäger W, Poschner S, Knosp E, Reinprecht A, Gruber A, Zeitlinger M, Antimicrob Agents Chemother. 2018 Jan 25;62(2). pii: e02164-17.
Poschner S, Maier-Salamon A, Zehl M, Wackerlig J, Dobusch D, Pachmann B, Sterlini KL, Jäger W, Front Pharmacol. 2017 Oct 5;8:699.
Influence of OATPs on Hepatic Disposition of Erlotinib Measured With Positron Emission Tomography
Bauer M, Matsuda A, Wulkersdorfer B, Philippe C, Traxl A, Özvegy-Laczka C, Stanek J, Nics L, Klebermass EM, Poschner S, Jäger W, Patik I, Bakos É, Szakács G, Wadsak W, Hacker M, Zeitlinger M, Langer O, Clin Pharmacol Ther. 2018 Jul;104(1):139-147.
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Journal Articles - 2017
Wulkersdorfer B, Jaros D, Eberl S, Poschner S, Jäger W, Cosentini E, Zeitlinger M, Schwameis R, Antimicrob Agents Chemother. 2017 Jul 25;61(8). pii: e00527-17.
Poschner S, Zehl M, Maier-Salamon A, Jäger W, J Pharm Biomed Anal. 2017 May 10;138:344-350.
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Conference Contributions
Pharmacokinetics of temozolomide in cerebrospinal fluid of children with malignant tumors - a pilot study
Büsker S, Peyrl A, Al Jaliali V, Jäger W, Poschner S, Ullah S, El Tabei L, Fuhr U, 15th Congress of the European Association for Clinical Pharmacology and Therapeutics, postponed to June 2022 (?), Athens, Greece.
Higher meropenem concentrations in brain tissue compared to cerebrospinal fluid in neurointensive care patients
Sanz Codina M, Hosmann A, Ritscher L, Burgmann H, Al Jalali V, Wulkersdorfer B, Wölfl-Duchek M, Jäger W, Poschner S, Plöchl W, Reinprecht A, Rössler K, Gruber A, Zeitlinger M, poster presentation, 31st European Congress of Clinical Microbiology & Infectious Diseases (ECCMID), July 2021, Online.
Development of intravascular microdialysis as a tool for therapeutic drug monitoring and intensive PK studies in children
Al Jalali V, Wulkersdorfer B, Matzneller P, Lackner E, Poschner S, Jaeger W, Zeitlinger M, poster presentation, 30th European Congress of Clinical Microbiology & Infectious Diseases (ECCMID), April 2020, Paris, France.
Black cohosh impairs steroid metabolism in human breast cancer cells: a targeted metabolomics approach
Poschner S, Maier-Salamon A, Wackerlig J, Dobusch D, Pachmann B, Banh SJ, Jäger W, oral presentation, 17th Austrian Proteomics and Metabolomics Research Symposium, September 2019, Salzburg, Austria.
Targeted metabolomics of steroids by LC-HRMS: application to platinum-sensitive and -resistant human ovarian cancer cells
Poschner S, Zehl M, Wackerlig J, Dobusch D, Castillo-Tong DC, Wolf A, Thalhammer T, Jäger W, oral presentation, 16th Austrian Proteomics and Metabolomics Research Symposium, August 2018, Vienna, Austria.
Resveratrol inhibits key steps of steroid metabolism in a human estrogen-receptor positive breast cancer model: impact on cellular Proliferation
Poschner S, Maier-Salamon A, Zehl M, Wackerlig J, Dobusch D, Pachmann B, Jäger W, oral presentation, 4th Congress on Steroid Research, July 2018, Seoul, South Korea.