Publications

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  • Journal Articles
    • Kiskova T., Demeckova V., Jendzelovska Z., Kiktava M., Venglovska K., Bohmdorfer M., Jager W., Thalhammer T. Nocturnal resveratrol administration inhibits chemically induced breast cancer formation in rats. J. Physiol. Pharmacol. 68: 867-875, 2017.
    • Böhmdorfer M., Szakmary A., Schiestl R.H., Vaquero J., Riha J., Brenner S., Thalhammer T., Szekeres T., Jäger W. Involvement of UDP-Glucuronosyltransferases and Sulfotransferases in the Excretion and Tissue Distribution of Resveratrol in Mice. Nutrients. 9: 1347, 2017.
    • Böhmdorfer M., Maier-Salamon A., Riha J., Brenner S., Höferl M., Jäger W. Interplay of drug metabolizing enzymes with cellular transporters. Wien Med. Wochenschr. 164: 461-471, 2014.
    • Riha J., Brenner S., Böhmdorfer M., Giessrigl B., Pignitter M. Schueller K., Thalhammer T., Stieger B., Somoza V., Szekeres T., Jäger W. Resveratrol and its major sulfated conjugates are substrates of organic anion transporting polypeptides (OATPs): Impact on growth of ZR-75-1 breast cancer cells. Mol. Nutr. Food Res. 58: 1830-1842, 2014.
    • Maier-Salamon A., Thalhammer T., Reznicek G., Böhmdorfer M., Zupkó I., Hartl A., Jaeger W. Cytochrome P450 3A-mediated metabolism of the topoisomerase I inhibitor9-aminocamptothecin: impact on cancer therapy. Int. J. Oncol. 45: 877-886, 2014.
    • Horvatits T., Kitzberger R., Drolz A., Zauner C., Jäger W., Böhmdorfer M., Kraff S., Fritsch A., Thalhammer F., Fuhrmann V., Schenk P. Pharmacokinetics of ganciclovir during continuous venovenous hemodiafiltration in critically ill patients. Antimicrob. Agents Chemother. 58: 94-101, 2014.
    • Maier-Salamon A., Böhmdorfer M., Riha J., Thalhammer T., Szekeres T., Jaeger W. Interplay between metabolism and transport of resveratrol. Ann. N Y Acad. Sci. 1290: 98-106, 2013.
    • Roth G.A., Sipos W., Höferl M., Böhmdorfer M., Schmidt EM., Hetz H., Schebesta K., Klaus D., Motal M., Jäger W., Krenn CG. The effect of the molecular adsorbent recirculating system on moxifloxacin and meropenem plasma levels. Acta Anaesthesiol. Scand. 57: 461-467, 2013.
    • Bauer M., Zeitlinger M., Todorut D., Böhmdorfer M., Müller M., Langer O., Jäger W. Pharmacokinetics of single ascending doses of the P-glycoprotein inhibitor tariquidar in healthy subjects. Pharmacology. 91: 12-19, 2013.
    • Sauermann R., Karch R., Kjellsson MC., Feurstein T., Püspök A., Langenberger H., Böhmdorfer M., Jäger W, Zeitlinger M. Good penetration of moxifloxacin into human abscesses. Pharmacology. 90: 146-150, 2012.
    • Tobudic S., Matzneller P., Stoiser B., Wenisch JM., Zeitlinger M., Vychytil A., Jaeger W., Boehmdorfer M., Reznicek G., Burgmann H. Pharmacokinetics of intraperitoneal and intravenous fosfomycin in automated peritoneal dialysis patients without peritonitis. Antimicrob. Agents Chemother. 56: 3992-3995, 2012.
    • Sauermann R., Feurstein T., Karch R., Kjellsson MC., Jäger W., Böhmdorfer M., Püspök A., Langenberger H., Wild T., Winkler S., Zeitlinger M. Abscess penetration of cefpirome: concentrations and simulated pharmacokinetic profiles in pus. Eur. J. Clin. Pharmacol. 68: 1419-1423, 2012.
    • Bauer M., Zeitlinger M., Karch R., Matzneller P., Stanek J., Jäger W., Böhmdorfer M., Wadsak W., Mitterhauser M., Bankstahl JP., Löscher W., Koepp M., Kuntner C., Müller M., Langer O. Pgp-mediated interaction between (R)-[(11)C]verapamil and tariquidar at the human blood-brain barrier: a comparison with rat data. Clin. Pharmacol. Ther. 91: 227-233, 2012.
    • Maier-Salamon A., Böhmdorfer M., Reznicek G., Thalhammer T., Szekeres T., Jaeger W. Hepatic glucuronidation of resveratrol: Interspecies comparison of enzyme kinetic profiles in human, mouse, rat and dog. Drug Metab Pharmacokinet. 26: 364-373, 2011.
    • Böhmdorfer M., Maier-Salamon A., Taferner B., Reznicek G., Thalhammer T., Hering S., Hüfner A., Schühly W., Jäger W. In vitro metabolism and disposition of honokiol in rat and human livers. J. Pharm. Sci. 100: 3506-3516, 2011.
    • Leitner JM., Meyer B., Fuhrmann V., Saria K., Zuba C., Jäger W., Böhmdorfer M., Thalhammer F. Multiple-dose pharmacokinetics of anidulafungin during continuous venovenous haemofiltration. J Antimicrob. Chemother. 66: 880-884, 2011.
    • Burian A., Wagner C., Stanek J., Manafi M., Böhmdorfer M., Jäger W., Zeitlinger M. Plasma protein binding may reduce antimicrobial activity by preventing intra-bacterial uptake of antibiotics, for example clindamycin. J. Antimicrob. Chemother. 66: 134-137, 2011.
    • Miksits M., Maier-Salamon A., Vo NT., Sulyok M., Schuhmacher R., Szekeres T., Jäger W. Glucuronidation of piceatannol by human liver microsomes: major role of UGT1A1, UGT1A8, and UGT1A10. J. Pharm. Pharmacol. 62: 47-54, 2010.
    • Miksits M, Wlcek K, Svoboda M, Thalhammer T, Ellinger I, Stefanzl G, Falany CN, Szekeres T, Jaeger W. Expression of sulfotransferases and sulfatases in human breast cancer: impact on resveratrol metabolism. Cancer Letters. 289: 237-245, 2010.
    • Miksits M, Wlcek K, Svoboda M, Kunert O, Haslinger E, Thalhammer T, Szekeres T, Jäger W. Antitumor activity of resveratrol and its sulfated metabolites against human breast cancer cells. Planta Medica. 75: 1227-1230, 2009.
    • Miksits, Michaela; Sulyok, Michael; Schuhmacher, Rainer; Szekeres, Thomas; Jaeger, Walter. In-vitro sulfation of piceatannol by human liver cytosol and recombinant sulfotransferases. Journal of Pharmacy and Pharmacology. 61: 185-191, 2009.
    • Murias, Marek; Miksits, Michaela; Aust, Sylvia; Spatzenegger, Margit; Thalhammer, Theresia; Szekeres, Thomas; Jaeger, Walter. Metabolism of resveratrol in breast cancer cell lines: Impact of sulfotransferase 1A1 expression on cell growth inhibition. Cancer Letters. 261: 172-182, 2008.
    • Fuhrmann, Valentin; Schenk, Peter; Jaeger, Walter; Miksits, Michaela; Kneidinger, Nikolaus; Warszawska, Joanna; Holzinger, Ulrike; Kitzberger, Reinhard; Thalhammer, Florian. Pharmacokinetics of voriconazole during continuous venovenous haemodiafiltration. Journal of Antimicrobial Chemotherapy. 60: 1085-1090, 2007.
    • Miksits, Michaela; Maier-Salamon, Alexandra; Aust, Sylvia; Thalhammer, Theresia; Reznicek, Gottfried; Kunert, O.; Haslinger, E.; Szekeres, T.; Jaeger, W. Sulfation of resveratrol in human liver: Evidence of a major role for the sulfotransferases SULT1A1 and SULT1E1. Xenobiotica. 35: 1101-1119, 2005.
    • Urpi-Sarda, Mireia; Jauregui, Olga; Lamuela-Raventos, Rosa Maria; Jaeger, Walter; Miksits, Michaela; Covas, Maria-Isabel; Andres-Lacueva, Cristina. Uptake of Diet Resveratrol into the Human Low-Density Lipoprotein. Identification and Quantification of ResveratrolMetabolites by Liquid Chromatography Coupled with Tandem Mass Spectrometry. Analytical Chemistry. 77: 3149-3155, 2005.
  • Conference Contributions
    • Riha J., Brenner S., Böhmdorfer M., Giessrigl B., Pignitter M., Schueller K., Thalhammer T., Stieger B., Somoza V., Szekeres T., Jäger W. Resveratrol and its sulfated conjugates are substrates of organic anion transporting polypeptides (OATPs): impact on breast cancer cell growth. The 19th International Symposium on Microsomes and Drug Oxidations and 12th European ISSX Meeting, 2012. Noordwijk aan Zee, Netherlands.
    • Kisková T., Garajová M., Böhmdorfer M., Svoboda M., Kassayová M., Bojková B., Orendáš P., Bobrov N., Jäger W., Thalhammer T. The phytohormone resveratrol and the pineal hormone melatonin in the rat mammary carcinogenesis. ISBN: 978-80-210-5442-4, 138-139, 2011. Conference on Cancer Research, Brno, Czech Republic.
    • Kisková T., Garajová M., Böhmdorfer M., Svoboda M., Kassayová M., Bojková B., Orendáš P., Bobrov N., Jäger W., Thalhammer T. Resveratrol and melatonin in the chemoprevention of mammary carcinogenesis in female Sprague-Dawley rats. 135-136, 2011. Week of Doctoral Studies, Nový Smokovec, Slovakia.
    • Miksits M., Wlcek K. Svoboda M., Thalhammer T., Jäger W. Expression of Sulfotransferases and Sulfatases in Human Breast Cancer: Impact on Resveratrol Metabolism. Scientia Pharmaceutica, 77 (1), SL-30, 2009. Oral presentation. 21st Scientific Congress of the Austrian Pharmaceutical Society, Vienna, Austria. 
    • Miksits M., Wlcek K., Svoboda M., Thalhammer T., Jaeger W. Antitumor activity of resveratrol and its sulfated metabolites against human breast cancer cells. 2009 AAPS Annual Meeting and Exposition, Los Angeles Convention Center, Los Angeles, CA, USA.
    •  Miksits M., Wlcek K., Sulyok M., Schuhmacher R., Jaeger W. In vitro sulfation of piceatannol by human liver cytosol and human recombinant sulfotransferases. Drug Metabolism Reviews, 40 (1), A179, 2008. 10th European Regional ISSX Meeting, Vienna, Austria.
    • Miksits M., Wlcek K., Svoboda M., Thalhammer T., Klimpfinger M., Jaeger W. Sulfation of resveratrol in human breast tumors and peritumoral tissues: role of sulfotransferases and sulfatases. Drug Metabolism Reviews, 39 (1), A157, 2007. 8th International ISSX Meeting, Sendai, Japan.
    •  Vo N., Miksits M., Maier-Salamon A., Szekeres T., Jaeger W. Metabolism of piceatannol in human liver microsomes: major role of UGT1A1, UGT1A8 and UGT1A10. Drug Metabolism Reviews, 39 (1), A263, 2007. 8th International ISSX Meeting, Sendai, Japan.
    • Miksits M., Maier-Salamon A., Aust S., Thalhammer T., Szekerers T., Jäger W. Sulfation of resveratrol, a polyphenolic compound found in grapes and wine, in human liver. Scientia Pharmaceutica, 74 (2), 17, 2006. Oral presentation. 19. Wissenschaftliche Tagung der Österreichischen Pharmazeutischen Gesellschaft, Innsbruck, Austria.
    •  Miksits M., Maier-Salamon A., Aust S., Thalhammer T., Szekeres T., Jaeger W. Sulfation of resveratrol in human liver: evidence of a major role for the sulfotransferases SULT1A1 and SULT1E1. Drug Metabolism Reviews, 37 (2), A732, 2005. 13th NA ISSX/20th JSSX Meeting, Maui, Hawaii.
    • Gehring E., Aust S., Miksits M., Thalhammer T., Senderowicz A., Laczka-Ozvegy C., Jaeger W. Transport of flavopiridol by ABCG2 in human breast cancer cell lines: impact on cytotoxicity. International Journal of Molecular Medicine, 14 (1), A124, 2004. 7th International ISSX Meeting, Vancouver, Canada.
    • Gehring E., Aust S., Miksits M., Thalhammer T., Senderowicz A., Laczka-Ozvegy C., Jaeger W. Transport of flavopiridol by ABCG2 in human breast cancer cell lines. Drug Metabolism Reviews, 36 (1), A107, 2004. 9th World Congress on Advances in Oncology and 7th International Symposium on Molecular Medicine, Hersonissos, Crete, Greece.